SRGN anticorps (C-Term)
Aperçu rapide pour SRGN anticorps (C-Term) (ABIN954731)
Antigène
Voir toutes SRGN AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 118-148, C-Term
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Specificité
- This antibody recognizes Serglycin at c-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Purified through a Protein A column followed by peptide affinity purification
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Immunogène
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 118-148aa) of human Serglycin.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SRGN (serglycin (SRGN))
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Autre désignation
- Serglycin / PRG1
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Sujet
- The SRGN gene encodes serglycin, a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.Synonyms: Hematopoetic proteoglycan core protein, Platelet proteoglycan core protein, SRGN, Secretory granule proteoglycan core protein
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ID gène
- 5552
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NCBI Accession
- NP_002718
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Pathways
- Maintenance of Protein Location
Antigène
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