SFTPB anticorps (Middle Region)

N° du produit ABIN954774

Détail du produit anti-SFTPB anticorps

Antigène: SFTPB (Surfactant Protein B (SFTPB))

Épitope: AA 128-158, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFTPB est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: Recognizes SFTPB (Center).

Purification: Protein A column followed by peptide Affinity purification

Immunogène: KLH conjugated synthetic peptide between 128-158 amino acids from the Central region of Human SFTPB Genename: SFTPB

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SFTPB

Antigène: SFTPB (Surfactant Protein B (SFTPB))

Autre désignation: SFTPB (SFTPB Produits)

Synonymes: anticorps PSP-B, anticorps SFTB3, anticorps SFTP3, anticorps SMDP1, anticorps SP-B, anticorps AI562151, anticorps SF-B, anticorps Sftp-3, anticorps Sftp3, anticorps Sp-b, anticorps SFTPB, anticorps sftpb, anticorps xSP-B, anticorps surfactant protein B, anticorps surfactant associated protein B, anticorps surfactant, pulmonary-associated protein B L homeolog, anticorps SFTPB, anticorps Sftpb, anticorps sftpb.L

Sujet: SFTPB is the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.Synonyms: 18 kDa pulmonary-surfactant protein, Pulmonary surfactant-associated protein B, Pulmonary surfactant-associated proteolipid SPL(Phe), SFTP3, SP-B, Surfactant protein B

ID gène: 6439

NCBI Accession: NP_000533