SP1 anticorps (C-Term)

N° du produit ABIN954894

Détail du produit anti-SP1 anticorps

Antigène: SP1 (Sp1 Transcription Factor (SP1))

Épitope: AA 684-715, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes SP1 / TSFP1 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 684-715aa) of human SP1 / TSFP1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SP1

Antigène: SP1 (Sp1 Transcription Factor (SP1))

Abstract: SP1 Produits

Synonymes: anticorps fc18h09, anticorps zgc:85950, anticorps wu:fc18h09, anticorps SP1, anticorps 1110003E12Rik, anticorps AA450830, anticorps AI845540, anticorps Sp1-1, anticorps sp1 transcription factor, anticorps Sp1 transcription factor, anticorps Sp1 transcription factor L homeolog, anticorps trans-acting transcription factor 1, anticorps sp1, anticorps SP1, anticorps Sp1, anticorps sp1.L

Sujet: Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.Synonyms: Transcription factor Sp1

ID gène: 6667

NCBI Accession: NP_003100

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction