SPACA1 anticorps (N-Term)
Aperçu rapide pour SPACA1 anticorps (N-Term) (ABIN954901)
Antigène
Voir toutes SPACA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 49-78, N-Term
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Specificité
- Recognizes SACA1 (N-term).
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Purification
- Protein A column followed by peptide Affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 49-78 amino acids from the N-terminal region of Human SACA1 Genename: SPACA1
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SPACA1 (Sperm Acrosome Associated 1 (SPACA1))
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Autre désignation
- SPACA1 / SAMP32
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Sujet
- The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.Synonyms: Sperm acrosomal membrane-associated protein 32, Sperm acrosome membrane-associated protein 1
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ID gène
- 81833
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NCBI Accession
- NP_112222
Antigène
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