SSRP1 anticorps (C-Term)

N° du produit ABIN954958

Cet anticorps Lapin Polyclonal détecte spécifiquement SSRP1 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour SSRP1 anticorps (C-Term) (ABIN954958)

Antigène: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSRP1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-SSRP1 anticorps

Épitope: AA 489-518, C-Term

Specificité: This antibody recognizes Human SSRP1 / FACT80 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of Human SSRP1. Genename: SSRP1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SSRP1

Antigène: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Autre désignation: SSRP1 / FACT80

Sujet: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.Synonyms: Chromatin-specific transcription elongation factor 80 kDa subunit, FACT 80 kDa subunit, FACT complex subunit SSRP1, FACTp80, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, T160

Poids moléculaire: 81075 Da

ID gène: 6749

NCBI Accession: NP_003137

Pathways: Chromatin Binding