STK38 anticorps (AA 365-466)

N° du produit ABIN954986

L’anticorps anti-STK38 Monoclonal Souris est utilisé pour la détection de STK38 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC (p) et EIA.

Aperçu rapide pour STK38 anticorps (AA 365-466) (ABIN954986)

Antigène: STK38 (serine/threonine Kinase 38 (STK38))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp STK38 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 6F1

Détail du produit anti-STK38 anticorps

Épitope: AA 365-466

Specificité: Recognizes STK38

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Protein A Chromatography

Immunogène: STK38 (AAH12085, 365 a.a. ~ 466 a.a) partial recombinant protein with GST tag.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur STK38

Antigène: STK38 (serine/threonine Kinase 38 (STK38))

Autre désignation: STK38

Sujet: STK38 contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.Synonyms: NDR1, Nuclear Dbf2-related kinase 1, Serine/threonine-protein kinase 38

ID gène: 11329

NCBI Accession: NP_009202

UniProt: Q15208