SYT1 anticorps
Aperçu rapide pour SYT1 anticorps (ABIN955025)
Antigène
Voir toutes SYT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes Synaptotagmin-1.
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Purification
- Affinity Chromatography using a peptide column.
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Immunogène
- Four different antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (NP_033332) and Human (NP_005630) gene products. Production: After repeated injections into the hens, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.4 mg/ml. Finally, equal volumes of each of the four affinity-purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized. Antibodies were affinity-purified and mixed in equal concentrations.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.4 mg/mL
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Buffer
- 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted in the dark at 2-8 °C.
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- SYT1 (Synaptotagmin I (SYT1))
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Autre désignation
- Synaptotagmin-1
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Sujet
- Human Synaptotagmin-1 is a 47,442 dalton protein (422 amino acids) associated with pre-synaptic terminals of the PNS and CNS. Synaptotagmin-1 binds calcium and initiates the fusion of vesicles with the pre-synaptic membrane. This protein is also believed to be the target of proteolytic activity associated with Botulinum neurotoxin A.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
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ID gène
- 6857
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NCBI Accession
- NP_001129277
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Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Antigène
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