TIFA anticorps (N-Term)
Aperçu rapide pour TIFA anticorps (N-Term) (ABIN955209)
Antigène
Voir toutes TIFA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 58-88, N-Term
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Specificité
- This antibody detects TIFA / T2BP (N-term).
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Protein A column followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 58~88 amino acids from the N-terminal region of human TIFA
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))
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Autre désignation
- TIFA / T2BP
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Sujet
- Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.Synonyms: Putative MAPK-activating protein PM14, Putative NF-kappa-B-activating protein 20, TRAF-interacting protein with FHA domain-containing protein A, TRAF2-binding protein
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ID gène
- 92610
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NCBI Accession
- NP_443096
Antigène
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