TIM3 anticorps (Biotin)

N° du produit ABIN955213

Cet anticorps Rat Monoclonal détecte spécifiquement TIM3 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour TIM3 anticorps (Biotin) (ABIN955213)

Antigène: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TIM3 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: 25F-1D6

Détail du produit anti-TIM3 anticorps (Biotin)

Specificité: Anti-mouse Tim-3 (T cell immunoglobulin domain, mucin domain 3) monoclonal antibody reacts with mouse Tim-3.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0,1 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN39 as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TIM3

Antigène: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Autre désignation: TIMD3 / HAVCR2

Classe de substances: Virus

Sujet: This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b+ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance.Synonyms: HAVCR-2, Hepatitis A virus cellular receptor 2, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3

ID gène: 171285

NCBI Accession: NP_599011

UniProt: Q8VIM0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints