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STING/TMEM173 anticorps (C-Term)
TMEM173
Reactivité: Humain, Souris
WB, FACS, EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-STING/TMEM173 anticorps
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Antigène
Voir toutes STING/TMEM173 (TMEM173) Anticorps
STING/TMEM173 (TMEM173)
(Transmembrane Protein 173 (TMEM173))
Épitope
Tous les épitopes à travers STING/TMEM173 Anticorps.
AA 318-348, C-Term
Reactivité
Toutes les réactivités sur STING/TMEM173 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur STING/TMEM173 Anticorps
Lapin
Clonalité
Toutes les clonalités sur STING/TMEM173 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers STING/TMEM173 Anticorps
Cet anticorp STING/TMEM173 est non-conjugé
Application
Tous les applications à travers STING/TMEM173 Anticorps.
Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
Specificité
This antibody detects TMEM173 / STING (C-term).
Réactivité croisée (Details)
Species reactivity (tested):Human, mouse
Purification
Protein A column followed by peptide affinity purification
Immunogène
KLH conjugated synthetic peptide between 318~348 amino acids from the C-terminal region of human TM173
Isotype
Ig Fraction
Top Product
Discover our top product TMEM173 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Détails sur STING/TMEM173
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Antigène
STING/TMEM173 (TMEM173)
(Transmembrane Protein 173 (TMEM173))
Autre désignation
TMEM173 / STING (TMEM173 Produits )
Synonymes
anticorps ERIS, anticorps MITA, anticorps MPYS, anticorps NET23, anticorps STING, anticorps 2610307O08Rik, anticorps Mita, anticorps RGD1562552, anticorps transmembrane protein 173, anticorps TMEM173, anticorps Tmem173
Sujet
Acts as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.Synonyms: MITA, Mediator of IRF3 activation, Stimulator of interferon genes protein, Transmembrane protein 173
ID gène
340061
NCBI Accession
NP_938023
Pathways
Activation of Innate immune Response
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