TOP3B anticorps (C-Term)
Aperçu rapide pour TOP3B anticorps (C-Term) (ABIN955293)
Antigène
Voir toutes TOP3B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 825-854, C-Term
-
Specificité
- This antibody detects TOP3B (C-term).
-
Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse
-
Purification
- Protein A column followed by peptide affinity purification
-
Immunogène
- KLH conjugated synthetic peptide between 825-854 amino acids from the C-terminal region of human TOP3B
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS with 0.09 % (W/V) sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
-
-
- TOP3B (Topoisomerase (DNA) III beta (TOP3B))
-
Autre désignation
- TOP3B
-
Sujet
- This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity, however, not all variants have been fully described.Synonyms: DNA topoisomerase 3-beta-1, DNA topoisomerase III beta-1, TOP3B1
-
ID gène
- 8940
-
NCBI Accession
- NP_003926
Antigène
-