TPSD1 anticorps (C-Term)
Aperçu rapide pour TPSD1 anticorps (C-Term) (ABIN955305)
Antigène
Voir toutes TPSD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 171-201, C-Term
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Specificité
- This antibody detects TPSD1 (C-term).
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Protein A column followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 171-201 amino acids from the C-terminal region of human TPSD1
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TPSD1 (Tryptase delta 1 (TPSD1))
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Autre désignation
- TPSD1
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Sujet
- Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.Synonyms: Tryptase delta
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ID gène
- 23430
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NCBI Accession
- NP_036349
Antigène
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