TRAF4 anticorps (C-Term)
Aperçu rapide pour TRAF4 anticorps (C-Term) (ABIN955308)
Antigène
Voir toutes TRAF4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 426-455, C-Term
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Specificité
- This antibody detects TRAF4 / RNF83 (C-term).
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Protein A column followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human TRAF4
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))
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Autre désignation
- TRAF4 / RNF83
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Sujet
- This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.Synonyms: CART1, Cysteine-rich domain associated with RING and Traf domains protein 1, MLN62, Malignant 62, RING finger protein 83, TNF receptor-associated factor 4
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ID gène
- 9618
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NCBI Accession
- NP_004286
Antigène
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