Transferrin anticorps

N° du produit ABIN955314

Cet anticorps anti-Transferrin Polyclonal Lapin (ABIN955314) détecte spécifiquement Transferrin dans IP et ID. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour Transferrin anticorps (ABIN955314)

Antigène: Transferrin (TF)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transferrin est non-conjugé

Application: Immunoprecipitation (IP), Immunodiffusion (ID)

Détail du produit anti-Transferrin anticorps

Specificité: This antibody is directed against Rat Transferrin.

Purification: This IgG fraction was isolated from a high titer antiserum by salt fractionation and DEAE ion exchange chromatography. It was titered against its immunogens, sterile filtered, and analyzed for immunoglobulin purity and protein concentration.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 7.8 mg IgG/ml

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur Transferrin

Antigène: Transferrin (TF)

Sujet: Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergens from serum.Synonyms: Beta-1 metal-binding globulin, Serotransferrin, Siderophilin

ID gène: 24825

NCBI Accession: NP_001013128

Pathways: Transition Metal Ion Homeostasis