UGDH anticorps (C-Term)

N° du produit ABIN955441

Cet anticorps Lapin Polyclonal détecte spécifiquement UGDH dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour UGDH anticorps (C-Term) (ABIN955441)

Antigène: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGDH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-UGDH anticorps

Épitope: AA 464-494, C-Term

Specificité: This antibody detects UGDH (C-term).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 464-494 amino acids from the C-terminal region of human UGDH

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Détails sur UGDH

Antigène: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Autre désignation: UGDH

Sujet: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.Synonyms: UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH

ID gène: 7358

NCBI Accession: NP_001171629

Pathways: Glycosaminoglycan Metabolic Process