WT1 anticorps (Middle Region)

N° du produit ABIN955586

Détail du produit anti-WT1 anticorps

Antigène: WT1 (Wilms Tumor 1 (WT1))

Épitope: AA 353-383, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Wilms tumor protein (Center).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 353-383 (E361) amino acids from the Central region of human WT1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: WT1 / Wilms Tumor Protein (WT1 Produits)

Synonymes: anticorps AWT1, anticorps EWS-WT1, anticorps GUD, anticorps NPHS4, anticorps WAGR, anticorps WIT-2, anticorps WT33, anticorps CWT1, anticorps WT1, anticorps XWT1a, anticorps wt-1, anticorps wt1, anticorps xWT1, anticorps WT-1, anticorps gud, anticorps wagr, anticorps wt33, anticorps xwt1, anticorps wit-2, anticorps si:ch211-160j6.3, anticorps zgc:152697, anticorps D630046I19Rik, anticorps Wt-1, anticorps XWT1b, anticorps XeWT1, anticorps Wilms tumor 1, anticorps Wilms tumor 1 S homeolog, anticorps wilms tumor 1b, anticorps Wilms tumor protein, anticorps Wilms tumor 1 homolog, anticorps Wilms tumor 1 L homeolog, anticorps WT1, anticorps wt1.S, anticorps wt1, anticorps wt1b, anticorps Wt1, anticorps wt1.L

Sujet: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq].Synonyms: WT33

ID gène: 7490

NCBI Accession: NP_000369

Pathways: Tube Formation