ZP4 anticorps (C-Term)

N° du produit ABIN955755

Détail du produit anti-ZP4 anticorps

Antigène: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Épitope: AA 452-482, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects ZP4 / ZPB (C-term).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 452-482 amino acids from the C-terminal region of human ZP4

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Détails sur ZP4

Antigène: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Autre désignation: ZP4 / ZPB (ZP4 Produits)

Synonymes: anticorps ZPB, anticorps xlZPB, anticorps lzpb-a, anticorps MGC154827, anticorps zbp, anticorps zp1, anticorps ZBP, anticorps TAC4, anticorps MGC154888, anticorps ZP1, anticorps Zp-4, anticorps ZP3-ALPHA, anticorps ZP, anticorps Zp-X, anticorps zona pellucida glycoprotein 4 S homeolog, anticorps zona pellucida glycoprotein 4, anticorps zona pellucida glycoprotein 4 L homeolog, anticorps zp4.S, anticorps zp4, anticorps ZP4, anticorps zp4.L, anticorps Zp4

Sujet: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4.Synonyms: Zona pellucida protein B, Zona pellucida sperm-binding protein 4

ID gène: 57829

NCBI Accession: NP_067009