CDNF anticorps

N° du produit ABIN956415

Cet anticorps anti-CDNF est un anticorps Souris Monoclonal détectant CDNF dans WB et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour CDNF anticorps (ABIN956415)

Antigène: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDNF est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 7D6

Détail du produit anti-CDNF anticorps

Specificité: Human, CDNF protein

Purification: purified by protein G affinity chromatography

Immunogène: Recombinant human CDNF protein produced usingCHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Purifiedfrom cell culture supernatant

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:64 000, WB: 1:4000. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format

Commentaires:

Synonym: ARMETL1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml

Buffer: PBS pH 7.4, with 0.1%

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Divide antibodyinto aliquots prior usage. Avoid multiple freeze-thaw cycles as productdegradation may result.

Stock: -20 °C

Stockage commentaire: This product is shipped in non-frozen liquid form in ambient conditions

Références pour anticorps anti-CDNF (ABIN956415)

Galli, Lindholm, Kontturi, Saarma, Urtti, Yliperttula: "Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy." dans: Cell transplantation, Vol. 28, Issue 4, pp. 413-424, (2020) (PubMed).

Détails sur CDNF

Antigène: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Autre désignation: CDNF

Sujet: CDNF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA- (Lindholmet al. 20007, Voutilainen et al., 2011) and MPTP-induced degeneration(Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson’sdisease. When administered after 6-OHDA or MPTP –lesioning it restores thedopaminergic function and prevents degeneration of dopamine neurons insubstantia nigra pars compacta

UniProt: Q49AH0