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YBX3/DBPA anticorps

YBX3 Reactivité: Borrelia burgdorferi WB, LF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN964622
  • Antigène Tous les produits YBX3/DBPA (YBX3)
    YBX3/DBPA (YBX3) (Y Box Binding Protein 3 (YBX3))
    Reactivité
    • 15
    • 2
    Borrelia burgdorferi
    Hôte
    • 17
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp YBX3/DBPA est non-conjugé
    Application
    • 17
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Lateral Flow (LF)
    Specificité
    This product was Protein-A purified and cross-adsorbed against MBP from monospecific antiserum by chromatography. This antibody is specific for Borrelia burgdorferi DbpA protein. A BLAST analysis was used to suggest cross-reactivity with DbpA from Borrelia burgdorferi sources based on 100% homology with the immunizing sequence. Partial reactivity is expected against Borrelia garinii sources based on 60-80% homology. Cross-reactivity with DbpA from other sources has not been determined.
    Attributs du produit
    This product is antibody made against DbpA, or Decorin Binding Protein A from the spirochete Borrelia burgdorferi, which is carried by Ixodes ticks. DbpA from other microbial organisms such as E. coli (ATP-dependent RNA helicase DbpA) are significantly different. The spirochete migrates from the tick midgut during tick feeding to tick salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix, enabling bacteria to colonize in mammalian tissues. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host.
    Immunogène
    MBP-fusion protein corresponding to Borrelia burgdorferi Dbp-A protein.
    Immunogen Type: RecombinantProtein
    Isotype
    IgG
  • Indications d'application
    This protein-A purified antibody has been tested for use in Western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 18.5 kDa in size corresponding to Borrelia burgdorferi DbpA protein by Western blotting in the appropriate cell lysate or extract.
    Commentaires

    Gene Name: dbpA, BB_A24

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Concentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Date de péremption
    12 months
  • Antigène
    YBX3/DBPA (YBX3) (Y Box Binding Protein 3 (YBX3))
    Autre désignation
    DBP A (YBX3 Produits)
    Synonymes
    anticorps CSDA, anticorps CSDA1, anticorps DBPA, anticorps ZONAB, anticorps csda, anticorps Csda, anticorps Dpba, anticorps MSY3, anticorps MSY4, anticorps Yb2, anticorps dbpA, anticorps oxyR, anticorps Dbpa, anticorps Y-box binding protein 3, anticorps Y-box binding protein 3 S homeolog, anticorps Y box protein 3, anticorps Y box binding protein 3, anticorps YBX3, anticorps ybx3.S, anticorps Ybx3
    Sujet
    This product is antibody made against DbpA, or Decorin Binding Protein A from the spirochete Borrelia burgdorferi, which is carried by Ixodes ticks. DbpA from other microbial organisms such as E. coli (ATP-dependent RNA helicase DbpA) are significantly different. The spirochete migrates from the tick midgut during tick feeding to tick salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix, enabling bacteria to colonize in mammalian tissues. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host.
    Synonyms: Decorin-binding Protein A, Borrelia burgdorferi dbpA
    ID gène
    1194347
    NCBI Accession
    NP_045697
    UniProt
    O50917
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