YBX1 anticorps

N° du produit ABIN964624

Détail du produit anti-YBX1 anticorps

Antigène: YBX1 (Y Box Binding Protein 1 (YBX1))

Reactivité: Borrelia burgdorferi

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YBX1 est non-conjugé

Application: Western Blotting (WB), Lateral Flow (LF)

Specificité: This product was Protein-A purified and cross-adsorbed against MBP from monospecific antiserum by chromatography. This antibody is specific for Borrelia burgdorferi DbpB protein. A BLAST analysis was used to suggest cross-reactivity with DbpB from B. burgdorferi and B. garinii sources based on 100% homology with the immunizing sequence. Cross-reactivity with DbpB from other sources has not been determined.

Attributs du produit: Decorin-binding protein B, or DbpB, binds to decorin, which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix enabling bacteria to colonize in mammalian tissues. The spirochete migrates from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host. Borrelia burgdorferi can colonize multiple tissues, and is capable of attachment to diverse cell types. The expression of decorin-binding protein (Dbp) A and/or DbpB, two B. burgdorferi surface proteins that bind GAGs, is sufficient to convert a high-passage nonadherent B. burgdorferi strain into one that efficiently binds 293 epithelial cells.

Purification: purified

Stérilité: Sterile filtered

Immunogène: MBP-fusion protein corresponding to Borrelia burgdorferi Dbp-B protein.
Immunogen Type: RecombinantProtein

Isotype: IgG

Information d'application

Indications d'application: This protein-A purified antibody has been tested for use in Western blotting. Specific conditions for reactivity should be optimized by the user. Expect a band approximately 17.9 kDa in size corresponding to Borrelia burgdorferi DbpB protein by Western blotting in the appropriate cell lysate or extract.

Commentaires:

Gene Name: dbpB, BB_A25

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Date de péremption: 12 months

Détails sur YBX1

Antigène: YBX1 (Y Box Binding Protein 1 (YBX1))

Autre désignation: DbpB (YBX1 Produits)

Synonymes: anticorps BP-8, anticorps CSDA2, anticorps CSDB, anticorps DBPB, anticorps MDR-NF1, anticorps NSEP-1, anticorps NSEP1, anticorps YB-1, anticorps YB1, anticorps Byb1, anticorps Cbfa, anticorps Dbpb, anticorps Ef1a, anticorps Msy1, anticorps Nsep1, anticorps Yb1, anticorps bp-8, anticorps csda2, anticorps csdb, anticorps dbpb, anticorps frgy1, anticorps mdr-nf1, anticorps nsep-1, anticorps nsep1, anticorps yb1, anticorps 1700102N10Rik, anticorps C79409, anticorps EF1A, anticorps MSY1, anticorps dbpB, anticorps mYB-1a, anticorps nuclease sensitive element binding protein 1, anticorps Y-box binding protein 1, anticorps Y box binding protein 1, anticorps Y-box binding protein 1 S homeolog, anticorps nuclease-sensitive element-binding protein 1, anticorps Y box protein 1, anticorps nsep1, anticorps YBX1, anticorps Ybx1, anticorps ybx1.S, anticorps LOC479011

Sujet: Decorin-binding protein B, or DbpB, binds to decorin, which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix enabling bacteria to colonize in mammalian tissues. The spirochete migrates from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host. Borrelia burgdorferi can colonize multiple tissues, and is capable of attachment to diverse cell types. The expression of decorin-binding protein (Dbp) A and/or DbpB, two B. burgdorferi surface proteins that bind GAGs, is sufficient to convert a high-passage nonadherent B. burgdorferi strain into one that efficiently binds 293 epithelial cells.
Synonyms: Decorin-binding protein B, Borrelia burgdorferi DbpB

ID gène: 1194341

NCBI Accession: NP_045698

UniProt: O50918

Pathways: Regulation of Muscle Cell Differentiation