Smooth Muscle Actin anticorps

N° du produit ABIN965507

L’anticorps Souris Monoclonal anti-Smooth Muscle Actin a été validé pour WB, IHC et ELISA. Il convient pour détecter Smooth Muscle Actin dans des échantillons de Humain, Rat, Souris et Singe. Il y a 1 publication disponible.

Aperçu rapide pour Smooth Muscle Actin anticorps (ABIN965507)

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Smooth Muscle Actin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4A4

Détail du produit anti-Smooth Muscle Actin anticorps

Purification: Ascitic fluid

Immunogène: Synthesized peptide of human ACTA2.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Smooth Muscle Actin (ABIN965507)

Morisaki, Akutsu, Ogino, Kondo, Yamanaka, Tsutsumi, Yoshimuta, Okajima, Matsuda, Minatoya, Sasaki, Tanaka, Ishibashi-Ueda, Morisaki: "Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD)." dans: Human mutation, Vol. 30, Issue 10, pp. 1406-11, (2009) (PubMed).

Détails sur Smooth Muscle Actin

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Autre désignation: ACTA2

Sujet: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms: AA76, ACTSA, ASmooth Muscle Actin.

Poids moléculaire: 42KDa

ID gène: 59

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development