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ADIPOQ anticorps (N-Term)

ADIPOQ Reactivité: Humain, Souris IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN965514
  • Antigène Voir toutes ADIPOQ Anticorps
    ADIPOQ (Adiponectin (ADIPOQ))
    Épitope
    • 18
    • 11
    • 11
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 55-69, N-Term
    Reactivité
    • 153
    • 63
    • 41
    • 17
    • 11
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 142
    • 67
    • 6
    • 3
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 150
    • 70
    Polyclonal
    Conjugué
    • 132
    • 34
    • 16
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADIPOQ est non-conjugé
    Application
    • 130
    • 101
    • 70
    • 35
    • 30
    • 27
    • 26
    • 21
    • 20
    • 12
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Purification
    Purified by antigen-specific affinity chromatography.
    Immunogène
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to residues 55-69 of human ADIPOQ(Adiponectin precursor)
    Top Product
    Discover our top product ADIPOQ Anticorps primaire
  • Indications d'application
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Arita, Kihara, Ouchi, Takahashi, Maeda, Miyagawa, Hotta, Shimomura, Nakamura, Miyaoka, Kuriyama, Nishida, Yamashita, Okubo, Matsubara, Muraguchi, Ohmoto, Funahashi, Matsuzawa: "Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity." dans: Biochemical and biophysical research communications, Vol. 257, Issue 1, pp. 79-83, (1999) (PubMed).

    Saito, Tobe, Minoshima, Asakawa, Sumiya, Yoda, Nakano, Shimizu, Tomita: "Organization of the gene for gelatin-binding protein (GBP28)." dans: Gene, Vol. 229, Issue 1-2, pp. 67-73, (1999) (PubMed).

    Schäffler, Orsó, Palitzsch, Büchler, Drobnik, Fürst, Schölmerich, Schmitz et al.: "The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for ..." dans: Biochemical and biophysical research communications, Vol. 260, Issue 2, pp. 416-25, (1999) (PubMed).

  • Antigène
    ADIPOQ (Adiponectin (ADIPOQ))
    Autre désignation
    ADIPOQ (ADIPOQ Produits)
    Synonymes
    anticorps ADP, anticorps DCAF9, anticorps 6720489L24Rik, anticorps 9330209L04Rik, anticorps Adp, anticorps Mamdc1, anticorps RNSVSP4U, anticorps SVSIV1, anticorps Svp4, anticorps ACDC, anticorps ACRP30, anticorps ADIPQTL1, anticorps ADPN, anticorps APM-1, anticorps APM1, anticorps GBP28, anticorps apM-1, anticorps 30kDa, anticorps APN, anticorps Acdc, anticorps Acrp30, anticorps Ad, anticorps adipo, anticorps apM1, anticorps ADN, anticorps acrpl, anticorps adipo-b, anticorps adipoql, anticorps zgc:153584, anticorps adipoq, anticorps WD and tetratricopeptide repeats 1, anticorps MAM domain containing glycosylphosphatidylinositol anchor 2, anticorps seminal vesicle secretory protein 4, anticorps adiponectin, C1Q and collagen domain containing, anticorps adiponectin, C1Q and collagen domain containing, b, anticorps adiponectin, C1Q and collagen domain containing L homeolog, anticorps WDTC1, anticorps Mdga2, anticorps Svs4, anticorps ADIPOQ, anticorps Adipoq, anticorps adipoqb, anticorps adipoq.L
    Sujet
    ADIPOQ (Adiponectin) is an important negative regulator in hematopoiesis and immunesystems. ADIPOQ may be involved in ending inflammatory responses through its inhibitory functions. ADIPOQ inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. It inhibits TNF-alpha-induced expression of endothelial adhesion molecules. ADIPOQ is involved in the control of fat metabolism and insulin sensitivity. Defects in ADIPOQ are the cause of adiponectin deficiency. The result is a very low concentration of plasma adiponectin. The decreased adiponectin plasma levels are associated with obesity insulin resistance, and diabetes type 2.
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