Apolipoprotein M anticorps
Aperçu rapide pour Apolipoprotein M anticorps (ABIN965578)
Antigène
Voir toutes Apolipoprotein M (APOM) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- TRX purified full length recombinant ApoM-GST expressed in E. Coli strain BL21 (DE3).
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Purification
- Antibodies are purified by protein A affinity chromatography
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Isotype
- IgG2a
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Indications d'application
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Western Blot: 1: 500- 1: 1,000
IF: 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. -
Restrictions
- For Research Use only
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Format
- Liquid
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Stock
- -20 °C
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: "Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis." dans: Nature medicine, Vol. 11, Issue 4, pp. 418-22, (2005) (PubMed).
: "Expression pattern of apolipoprotein M during mouse and human embryogenesis." dans: Acta histochemica, Vol. 106, Issue 2, pp. 123-8, (2004) (PubMed).
: "A novel human apolipoprotein (apoM)." dans: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31286-90, (1999) (PubMed).
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- Apolipoprotein M (APOM)
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Autre désignation
- ApoM
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Sujet
- Apolipoprotein M (ApoM) is a member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. It is positively related to leptin. It is mainly expressed in liver and kidney. ApoM is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. It is important for the formation of prebeta-HDL and cholesterol efflux to HDL, and thereby inhibits formation of atherosclerotic lesions.
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ID gène
- 55937
Antigène
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