ARL1 anticorps (N-Term)

N° du produit ABIN965592

Cité dans 2 publications. Cet anticorps anti-ARL1 Polyclonal Lapin (ABIN965592) détecte spécifiquement ARL1 dans IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ARL1 anticorps (N-Term) (ABIN965592)

Antigène: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARL1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-ARL1 anticorps

Épitope: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ARL1(ADP-ribosylation factor-like protein 1)

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-ARL1 (ABIN965592)

Van Valkenburgh, Shern, Sharer, Zhu, Kahn: "ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins." dans: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22826-37, (2001) (PubMed).

Hong, Lee, Patton, Lin, Moss, Vaughan: "Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1)." dans: The Journal of biological chemistry, Vol. 273, Issue 25, pp. 15872-6, (1998) (PubMed).

Détails sur ARL1

Antigène: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Autre désignation: ARL1

Sujet: ARL1(ADP-ribosylation factor-like protein 1) belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Recent data show that Arl1 regulates the membrane recruitment of Golgin-97, which plays a role in transport from the endosome to the trans-Golgi network.