BCL anticorps

N° du produit ABIN965648

L’anticorps Lapin Polyclonal anti- a été validé pour IHC. Il convient pour détecter dans des échantillons de Humain. Il y a 5+ publications disponibles.

Aperçu rapide pour BCL anticorps (ABIN965648)

Antigène: BCL

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunohistochemistry (IHC)

Détail du produit

Specificité: BCL-2 (Ab-56) antibody detects endogenous levels of total BCL-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: This antiserum was produced against synthesized non-phosphopeptide derived from human BCL-2 around the phosphorylation site of threonine 56 (G-H-TP-P-H).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Référence

Huang, Cidlowski: "Phosphorylation status modulates Bcl-2 function during glucocorticoid-induced apoptosis in T lymphocytes." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 16, Issue 8, pp. 825-32, (2002) (PubMed).

Deng, Xiao, Lang, Gao, Ruvolo, May: "Novel role for JNK as a stress-activated Bcl2 kinase." dans: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 23681-8, (2001) (PubMed).

Yamamoto, Ichijo, Korsmeyer: "BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M." dans: Molecular and cellular biology, Vol. 19, Issue 12, pp. 8469-78, (2000) (PubMed).

Siegert, Robbins: "Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250." dans: Molecular and cellular biology, Vol. 19, Issue 1, pp. 846-54, (1999) (PubMed).

Ling, Tornos, Perez-Soler: "Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis." dans: The Journal of biological chemistry, Vol. 273, Issue 30, pp. 18984-91, (1998) (PubMed).

Détail du antigène

Antigène: BCL