Endoglin anticorps

N° du produit ABIN965762

2+ publications sont disponibles pour ce produit. L’anticorps anti-Endoglin Monoclonal produit chez le Souris a été validé pour WB, FACS, IHC, ELISA et IF. Il convient pour la détection de Endoglin dans des échantillons provenant de Humain. }

Aperçu rapide pour Endoglin anticorps (ABIN965762)

Antigène: Endoglin (ENG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Endoglin est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 3A9

Détail du produit anti-Endoglin anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CD105 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Endoglin (ABIN965762)

Fujita, Ewing, Chan, Mangold, Partin, Isaacs, Pavlovich: "Endoglin (CD105) as a urinary and serum marker of prostate cancer." dans: International journal of cancer. Journal international du cancer, Vol. 124, Issue 3, pp. 664-9, (2008) (PubMed).

Sun: "Pharmacophore-based virtual screening." dans: Current medicinal chemistry, Vol. 15, Issue 10, pp. 1018-24, (2008) (PubMed).

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: CD105

Sujet: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Synonyms: ENG, END, ORW, HHT1, ORW1, CD105, FLJ41744

Poids moléculaire: 71kDa

ID gène: 2022