CfPV-2 E7 (N-Term) anticorps

N° du produit ABIN965877

Détail du produit

Antigène: CfPV-2 E7

Épitope: N-Term

Reactivité: Papillomavirus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC)

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Dog Canine papillomavirus 2 CfPV-2 E7 protein

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Référence

Yuan, Ghim, Newsome, Apolinario, Olcese, Martin, Delius, Felsburg, Jenson, Schlegel: "An epidermotropic canine papillomavirus with malignant potential contains an E5 gene and establishes a unique genus." dans: Virology, Vol. 359, Issue 1, pp. 28-36, (2007) (PubMed).

Détail du antigène

Antigène: CfPV-2 E7

Classe de substances: Viral Protein

Sujet: CfPV-2 has unique biological features, it induces papillomas on footpads and interdigital regions which, if infection is persistent, can progress to highly metastatic squamous cell carcinoma. CfPV-2 does not induce oral papillomas in immunocompetent animals and antibodies generated against COPV and CfPV-2 are type-specific. The availability of a new canine papillomavirus with differing genetic and biological properties now makes it possible to study type-specific host immune responses, tissue tropism and the comparative analysis of viral gene functions in the dog.