CHD3 anticorps

N° du produit ABIN965879

Il existe 3+ publications pour ce produit. L’anticorps anti-CHD3 Monoclonal Souris est utilisé pour la détection de CHD3 dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC, IF, ELISA et FACS.

Aperçu rapide pour CHD3 anticorps (ABIN965879)

Antigène: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CHD3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)

Clone: 2G4

Détail du produit anti-CHD3 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CHD3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-CHD3 (ABIN965879)

Burd, Kinyamu, Miller, Archer: "UV radiation regulates Mi-2 through protein translation and stability." dans: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).

Goehler, Lalowski, Stelzl, Waelter, Stroedicke, Worm, Droege, Lindenberg, Knoblich, Haenig, Herbst, Suopanki, Scherzinger, Abraham, Bauer, Hasenbank, Fritzsche, Ludewig, Büssow, Buessow, Coleman et al.: "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. ..." dans: Molecular cell, Vol. 15, Issue 6, pp. 853-65, (2004) (PubMed).

Lepesheva, Virus, Waterman: "Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function." dans: Biochemistry, Vol. 42, Issue 30, pp. 9091-101, (2003) (PubMed).

Détails sur CHD3

Antigène: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Autre désignation: CHD3

Sujet: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Synonyms: ZFH, Mi-2a, Mi2ALPHA, CHD3

Poids moléculaire: 226kDa

ID gène: 1107