Decorin anticorps (Isoform d)

N° du produit ABIN965978

Détail du produit anti-Decorin anticorps

Antigène: Decorin (DCN)

Épitope: Isoform d

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Decorin est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human DCN (decorin isoform d precursor) Or dermatan sulphate proteoglycans II, bone proteoglycan II, proteoglycan core protein, small leucinerich protein 1B.

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-Decorin (ABIN965978)

Al-Mansi, Abdel: "Recovery of nickel oxide from spent catalyst." dans: Waste management (New York, N.Y.), Vol. 22, Issue 1, pp. 85-90, (2002) (PubMed).

Détails sur Decorin

Antigène: Decorin (DCN)

Autre désignation: DCN (DCN Produits)

Synonymes: anticorps CSCD, anticorps DSPG2, anticorps PG40, anticorps PGII, anticorps PGS2, anticorps SLRR1B, anticorps DC, anticorps mDcn, anticorps cscd, anticorps dspg2, anticorps pg40, anticorps pgii, anticorps pgs2, anticorps slrr1b, anticorps decorin, anticorps decorin L homeolog, anticorps DCN, anticorps Dcn, anticorps dcn.L, anticorps dcn

Sujet: The DCN(decorin isoform d) is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils,and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. The decorin supports adhesion and activation of human platelets. The decorin can disrupt glucose and TGFbeta/Smad-dependent transcription in mesangial cells through a mechanism that involves an increase in Ca(2+) signalling, the activation of Ca(2+)/calmodulin-dependent protein kinase II and phosphorylation of Smad2

Pathways: Glycosaminoglycan Metabolic Process