GSTP1 anticorps

N° du produit ABIN966240

Détail du produit anti-GSTP1 anticorps

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp GSTP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-GSTP1 (ABIN966240)

Lin, Nelson: "Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells." dans: Cancer research, Vol. 63, Issue 2, pp. 498-504, (2003) (PubMed).

Satoh, Itoh, Yamamoto, Tanaka, Hayakari, Ookawa, Yamazaki, Sato, Tsuchida, Hatayama: "Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells." dans: Carcinogenesis, Vol. 23, Issue 3, pp. 457-62, (2002) (PubMed).

Détails sur GSTP1

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Autre désignation: GSTP1 (GSTP1 Produits)

Synonymes: anticorps DFN7, anticorps FAEES3, anticorps GST3, anticorps GSTP, anticorps PI, anticorps GST-P, anticorps Gst3, anticorps Gstp, anticorps Gstp2, anticorps gst-Pi, anticorps GstpiB, anticorps glutathione S-transferase P-like, anticorps glutathione S-transferase pi 1, anticorps glutathione S-transferase pi 1 L homeolog, anticorps glutathione S-transferase, pi 1, anticorps LOC100739163, anticorps GSTP1, anticorps Gstp1, anticorps LOC100861197, anticorps gstp1.L

Sujet: GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.

ID gène: 2950

Pathways: Cellular Response to Molecule of Bacterial Origin