HAND1 anticorps (AA 90-190)

N° du produit ABIN966248

Il existe 1 publication pour ce produit. L’anticorps anti-HAND1 Monoclonal Souris est utilisé pour la détection de HAND1 dans des échantillons de Humain. Il a été validé pour ELISA et WB.

Aperçu rapide pour HAND1 anticorps (AA 90-190) (ABIN966248)

Antigène: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HAND1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Clone: 8E7A11-8C2F4

Détail du produit anti-HAND1 anticorps

Épitope: AA 90-190

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of HAND1 (aa90-190) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-HAND1 (ABIN966248)

Firulli, Howard, McDaid, McIlreavey, Dionne, Centonze, Cserjesi, Virshup, Firulli: "PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation." dans: Molecular cell, Vol. 12, Issue 5, pp. 1225-37, (2003) (PubMed).

Détails sur HAND1

Antigène: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Autre désignation: HAND1

Sujet: HAND1: heart and neural crest derivatives expressed 1. The protein encoded by this gene belongs to the basic helixloop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Synonyms: Hxt, eHand, Thing1, bHLHa27

ID gène: 9421

Pathways: Tube Formation