HPS1 anticorps

N° du produit ABIN966298

Cet anticorps Souris Monoclonal détecte spécifiquement HPS1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour HPS1 anticorps (ABIN966298)

Antigène: HPS1 (Hermansky-Pudlak Syndrome 1 (HPS1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HPS1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 5G12G2

Détail du produit anti-HPS1 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of HPS1 expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-HPS1 (ABIN966298)

Kobashi, Yoshida, Miyashita, Niki, Matsushima: "Hermansky-Pudlak syndrome with interstitial pneumonia without mutation of HSP1 gene." dans: Internal medicine (Tokyo, Japan), Vol. 44, Issue 6, pp. 616-21, (2005) (PubMed).

Nazarian, Falcón-Pérez, DellAngelica: "Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8770-5, (2003) (PubMed).

Détails sur HPS1

Antigène: HPS1 (Hermansky-Pudlak Syndrome 1 (HPS1))

Autre désignation: HPS1

Sujet: Hermansky-Pudlak syndrome 1. This protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Multiple transcript variants encoding distinct isoforms have been identified for this gene, the full-length sequences of some of these have not been determined yet.
Synonyms: HPS, MGC5277, HPS1

ID gène: 3257