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KLHL22 anticorps

Cet anticorps anti-KLHL22 est un anticorps Souris Monoclonal détectant KLHL22 dans WB et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.
N° du produit ABIN966459

Aperçu rapide pour KLHL22 anticorps (ABIN966459)

Antigène

Voir toutes KLHL22 Anticorps
KLHL22 (Kelch-Like 22 (KLHL22))

Reactivité

  • 33
  • 30
  • 17
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 35
  • 10
Souris

Clonalité

  • 36
  • 9
Monoclonal

Conjugué

  • 15
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp KLHL22 est non-conjugé

Application

  • 34
  • 18
  • 13
  • 13
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)

Clone

7B10
  • Purification

    Ascitic fluid

    Immunogène

    Purified recombinant fragment of human KLHL22 expressed in E. Coli.

    Isotype

    IgG1
  • Indications d'application

    Western Bloting: 1/500 - 1/2000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C
  • Maruyama, Sugano: "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides." dans: Gene, Vol. 138, Issue 1-2, pp. 171-4, (1994) (PubMed).

  • Antigène

    KLHL22 (Kelch-Like 22 (KLHL22))

    Autre désignation

    KLHL22

    Sujet

    KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophilakelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.
    Synonyms: KELCHL, KLHL22

    Poids moléculaire

    72kDa

    ID gène

    84861
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