Laminin anticorps

N° du produit ABIN966476

3+ publications sont disponibles pour ce produit. L’anticorps anti-Laminin Monoclonal produit chez le Souris a été validé pour WB et IHC (p). Il convient pour la détection de Laminin dans des échantillons provenant de Humain. }

Aperçu rapide pour Laminin anticorps (ABIN966476)

Antigène: Laminin (LN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Laminin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: Lam-26

Détail du produit anti-Laminin anticorps

Réactivité croisée: Chat, Porc

Réactivité croisée (Details): No cross reactivity with other proteins.

Immunogène: Human laminin.

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 1.2 % sodium acetate or neutral PBS. If 1 mL of PBS is used, the antibody concentration will be 100 µg/mL.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

Références pour anticorps anti-Laminin (ABIN966476)

Zhang, Vuolteenaho, Tryggvason: "Structure of the human laminin alpha2-chain gene (LAMA2), which is affected in congenital muscular dystrophy." dans: The Journal of biological chemistry, Vol. 271, Issue 44, pp. 27664-9, (1996) (PubMed).

Arahata, Hayashi, Mizuno, Yoshida, Ozawa: "Dystrophin-associated glycoprotein and dystrophin co-localisation at sarcolemma in Fukuyama congenital muscular dystrophy." dans: Lancet (London, England), Vol. 342, Issue 8871, pp. 623-4, (1993) (PubMed).

Ehrig, Leivo, Argraves, Ruoslahti, Engvall: "Merosin, a tissue-specific basement membrane protein, is a laminin-like protein." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 9, pp. 3264-8, (1990) (PubMed).

Détails sur Laminin

Antigène: Laminin (LN)

Autre désignation: Laminin

Sujet: Laminin is a heterotrimeric extracellular matrix protein consisting of 3 chains: alpha-1,beta-1 and gamma-1, formerly called beta-2 (LAMA2). This gene is over 260, 000 base pairs and contains 64 exons. Laminin is similar with merosin, a basement membrane-associated protein found in placenta, striated muscle, and peripheral nerve, and both of them are members of the same family of basement membrane proteins. And merosin is the same as laminin M, a striated muscle-specific, basal-lamina-associated protein, it may play a primary role in the pathogenesis of that disorder.

ID gène: 284217, 16772, 316758

UniProt: P02469, P15800, Q61292, D3ZQN7, P07942, Q60675, P19137, P55268, D4A409, P25391, F1M614, P24043