MMP10 anticorps (C-Term)

N° du produit ABIN966586

Cet anticorps Polyclonal détecte spécifiquement MMP10 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour MMP10 anticorps (C-Term) (ABIN966586)

Antigène: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MMP10 anticorps

Épitope: AA 410-422, C-Term

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminal of human MMP-10 (410-422 aa), identical to the related mouse and rat sequence.

Information d'application

Indications d'application: WB: The detection limit for MMP-10 is approximately 2.5ng/lane under non-reducing and reducing conditions.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Stock: -20 °C

Références pour anticorps anti-MMP10 (ABIN966586)

Jung, Warter, Rumpler: "Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization." dans: Annales de génétique, Vol. 33, Issue 1, pp. 21-3, (1990) (PubMed).

Muller, Quantin, Gesnel, Millon-Collard, Abecassis, Breathnach: "The collagenase gene family in humans consists of at least four members." dans: The Biochemical journal, Vol. 253, Issue 1, pp. 187-92, (1988) (PubMed).

Détails sur MMP10

Antigène: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Autre désignation: MMP-10

Sujet: Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.