DOK1 anticorps

N° du produit ABIN966767

Il existe 4+ publications pour ce produit. L’anticorps anti-DOK1 Polyclonal Lapin est utilisé pour la détection de DOK1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC.

Aperçu rapide pour DOK1 anticorps (ABIN966767)

Antigène: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-DOK1 anticorps

Specificité: P62Dok (Ab-398) antibody detects endogenous levels of total p62Dok protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 398 (E-G-YP-E-L).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-DOK1 (ABIN966767)

Simoncic, Bourdeau, Lee-Loy, Rohrschneider, Tremblay, Stanley, McGlade: "T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation." dans: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4149-60, (2006) (PubMed).

Yopp, Ochando, Mao, Ledgerwood, Ding, Bromberg: "Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 5, pp. 2913-24, (2005) (PubMed).

Dubé, Cheng, Tremblay: "The role of protein tyrosine phosphatase 1B in Ras signaling." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 7, pp. 1834-9, (2004) (PubMed).

Wick, Dong, Hu, Langlais, Liu: "Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt." dans: The Journal of biological chemistry, Vol. 276, Issue 46, pp. 42843-50, (2001) (PubMed).

Détails sur DOK1

Antigène: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Autre désignation: p62Dok