RL2 (N-Term) anticorps

N° du produit ABIN966970

Détail du produit

Antigène: RL2

Épitope: N-Term

Reactivité: Herpes Simplex Virus (HSV)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC)

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Human herpesvirus 2 RL2 (Trans-acting transcriptional protein ICP0)

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Référence

McGeoch, Cunningham, McIntyre, Dolan: "Comparative sequence analysis of the long repeat regions and adjoining parts of the long unique regions in the genomes of herpes simplex viruses types 1 and 2." dans: The Journal of general virology, Vol. 72 ( Pt 12), pp. 3057-75, (1992) (PubMed).

Barnett, Dolan, Telford, Davison, McGeoch: "A novel herpes simplex virus gene (UL49A) encodes a putative membrane protein with counterparts in other herpesviruses." dans: The Journal of general virology, Vol. 73 ( Pt 8), pp. 2167-71, (1992) (PubMed).

Everett, Fenwick: "Comparative DNA sequence analysis of the host shutoff genes of different strains of herpes simplex virus: type 2 strain HG52 encodes a truncated UL41 product." dans: The Journal of general virology, Vol. 71 ( Pt 6), pp. 1387-90, (1990) (PubMed).

McGeoch, Moss, McNab, Frame: "DNA sequence and genetic content of the HindIII l region in the short unique component of the herpes simplex virus type 2 genome: identification of the gene encoding glycoprotein G, and evolutionary comparisons." dans: The Journal of general virology, Vol. 68 ( Pt 1), pp. 19-38, (1987) (PubMed).

Détail du antigène

Antigène: RL2

Classe de substances: Viral Protein

Sujet: RL2 (Trans-acting transcriptional protein ICP0) contains 1 RING-type zinc finger. The RING-finger domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc, defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H) -X2-C-X(4-48) C-X2-C and RL2 also contains HRD1, HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones ].