Reticulon 3 anticorps

N° du produit ABIN966979

Cet anticorps Souris Monoclonal détecte spécifiquement Reticulon 3 dans WB et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour Reticulon 3 anticorps (ABIN966979)

Antigène: Reticulon 3 (RTN3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Reticulon 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1E11

Détail du produit anti-Reticulon 3 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of RTN3 expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application: Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Reticulon 3 (ABIN966979)

Wakana, Koyama, Nakajima, Hatsuzawa, Nagahama, Tani, Hauri, Melançon, Tagaya: "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi." dans: Biochemical and biophysical research communications, Vol. 334, Issue 4, pp. 1198-205, (2005) (PubMed).

Brain, Wilson, Johnson, Sanderson, Bestari, Hanson, Sibley, Solomon: "Effects of a mixture of tetracyclines to Lemna gibba and Myriophyllum sibiricum evaluated in aquatic microcosms." dans: Environmental pollution (Barking, Essex : 1987), Vol. 138, Issue 3, pp. 425-42, (2005) (PubMed).

Cai, Saiyin, Lin, Zhang, Tang, Pan, Yu: "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain." dans: Brain research. Molecular brain research, Vol. 138, Issue 2, pp. 236-43, (2005) (PubMed).

Oertle, Klinger, Stuermer, Schwab: "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 10, pp. 1238-47, (2003) (PubMed).

Détails sur Reticulon 3

Antigène: Reticulon 3 (RTN3)

Autre désignation: RTN3

Sujet: RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Synonyms: HAP, ASYIP, NSPL2, NSPLII, RTN3-A1

Poids moléculaire: 113kDa

ID gène: 10313