SasG anticorps (C-Term)

N° du produit ABIN966995

L’anticorps anti-SasG Polyclonal produit chez le Lapin a été validé pour IHC. Il convient pour la détection de SasG dans des échantillons provenant de Staphylococcus aureus. }

Aperçu rapide pour SasG anticorps (C-Term) (ABIN966995)

Antigène: SasG (SASG) (SasG Gene Product (SASG))

Reactivité: Staphylococcus aureus

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunohistochemistry (IHC)

Détail du produit anti-SasG anticorps

Épitope: C-Term

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Bacteria: Staphylococcus aureus SasG (Surface protein G)

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Détails sur SasG

Antigène: SasG (SASG) (SasG Gene Product (SASG))

Autre désignation: SasG

Sujet: SasG (Surface protein G) promotes adhesion of bacterial cells to human squamous nasal epithelial cells, a phenomenon which is likely to be important in nasal colonization. Forms short, extremely dense and thin fibrils all over the bacterial surface. SasG (Surface protein G) does not bind to either buccal cells or non-differentiated keratinocytes. SasG (Surface protein G) promotes cellular aggregation leading to biofilm formation. SasG (Surface protein G) is secreted, cell wall protein. It is produced during infection of the human host. SasG (Surface protein G) does not bind to immobilized fibrinogen, fibronectin, IgG, human epidermal keratin, collagen, vWF, laminin, heparan sulfate and submaxillary mucin. When sasG is expressed at high levels, it inhibits adhesion of S.aureus to the ligands fibrinogen, fibronectin, cytokeratin 10 and IgG. This inhibitory effect depends on the number of G5 repeats present in the protein, since shorter variants do not present this phenotype. Biofilm formation is ica-independent, relying only on the level of expression of the protein and the number of G5 repeats.