SCD anticorps

N° du produit ABIN966997

Cet anticorps Monoclonal détecte spécifiquement SCD dans WB, ELISA, IHC et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour SCD anticorps (ABIN966997)

Antigène: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Reactivité: Humain, Souris

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp SCD est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-SCD anticorps

Specificité: Full length recombinant protein. Reacts with human and mouse proteins.

Isotype: IgG2b

Information d'application

Indications d'application: Western blot, ELISA, IP, and IHC in obesity research.

Restrictions: For Research Use only

Stockage

Concentration: 1mg/ml

Buffer: PBS, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SCD

Antigène: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Autre désignation: SCD1

Sujet: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa, ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders.

ID gène: 20249

Pathways: Brown Fat Cell Differentiation