Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) anticorps

Détails pour le produit réf. ABIN966997, Fournisseur: Connectez-vous pour afficher
Antigène
  • FADS5
  • MSTP008
  • SCD1
  • SCDOS
  • AA589638
  • AI265570
  • Scd
  • Scd-1
  • ab
  • SCD
  • Scd2
  • fads5
  • scd1
  • scdos
  • F27J15.17
  • F27J15_17
  • STOMATAL CYTOKINESIS-DEFECTIVE 1
  • cds2
  • desaturase
  • stearoyl-CoA desaturase
  • acyl-CoA desaturase
  • Acyl-CoA desaturase
  • stearoyl-Coenzyme A desaturase 1
  • stearoyl-CoA desaturase (delta-9-desaturase)
  • stearoyl-Coenzyme A desaturase 2
  • stearoyl-CoA desaturase (delta-9-desaturase) S homeolog
  • stomatal cytokinesis defective / SCD1 protein (SCD1)
  • acyl-CoA desaturase-like
  • SCD
  • CIMG_08158
  • VIBHAR_RS23280
  • acod
  • Scd1
  • Scd
  • scd
  • LOC100346561
  • Scd2
  • scd.S
  • SCD1
  • LOC100719661
  • LOC101835884
  • LOC109101093
Reactivité
Humain, Souris
83
30
27
5
4
2
2
2
1
1
1
Hôte
63
21
9
1
Clonalité
Monoclonal
Conjugué
Inconjugué
4
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
50
39
36
16
15
13
12
12
6
4
2
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Isotype IgG2b
Specificité Full length recombinant protein. Reacts with human and mouse proteins.
Antigène
Autre désignation SCD1 (SCD Antibody Extrait)
Sujet Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa, ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders.
ID gène 20249
Pathways Brown Fat Cell Differentiation
Indications d'application Western blot, ELISA, IP, and IHC in obesity research.
Restrictions For Research Use only
Concentration 1mg/ml
Buffer PBS, pH 7.4
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
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