SETDB1 anticorps

N° du produit ABIN967016

Il existe 1 publication pour ce produit. L’anticorps anti-SETDB1 Monoclonal Souris est utilisé pour la détection de SETDB1 dans des échantillons de Humain, Souris et Singe. Il a été validé pour WB et ELISA.

Aperçu rapide pour SETDB1 anticorps (ABIN967016)

Antigène: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Reactivité: Humain, Souris, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SETDB1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 5H6D4

Détail du produit anti-SETDB1 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human SETDB1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-SETDB1 (ABIN967016)

Gao, Yu, Bi, Jiang, Cui, Sun, Ma: "Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression." dans: Molecular and cellular biochemistry, Vol. 305, Issue 1-2, pp. 35-44, (2007) (PubMed).

Détails sur SETDB1

Antigène: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Autre désignation: SETDB1

Sujet: This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-Lmethionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression.
Tissue specificity: Widely expressed. High expression in testis.
Synonyms: ESET, KG1T, KMT1E, KIAA0067, H3-K9-HMTase4, SETDB1

Poids moléculaire: 180kDa

ID gène: 9869