TIMP3 anticorps (N-Term)

N° du produit ABIN967183

Cet anticorps Lapin Polyclonal détecte spécifiquement TIMP3 dans IHC. Il présente une réactivité envers Humain et Xenopus laevis.

Aperçu rapide pour TIMP3 anticorps (N-Term) (ABIN967183)

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reactivité: Humain, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP3 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-TIMP3 anticorps

Épitope: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of African clawed frog TIMP3(Metalloproteinase inhibitor 3 precursor)

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TIMP3

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Autre désignation: TIMP3

Sujet: TIMP3(Metalloproteinase inhibitor 3) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. TIMP3 may form part of a tissue-specific acute response to remodeling stimuli. TIMP3 is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. Defects in TIMP3 are the cause of Sorsby's fundus dystrophy (SFD). SFD is a rare autosomal dominant macular disorder with an age of onset in the fourth decade. It is characterized by loss of central vision from subretinal neovascularization and atrophy of the occular tissues.