TRIM22 anticorps (C-Term)
Aperçu rapide pour TRIM22 anticorps (C-Term) (ABIN967202)
Antigène
Voir toutes TRIM22 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Immunogène
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human TRIM22 (Tripartite motif-containing protein 22)
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Restrictions
- For Research Use only
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Stock
- 4 °C
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: "B30.2/SPRY domain in tripartite motif-containing 22 is essential for the formation of distinct nuclear bodies." dans: FEBS letters, Vol. 583, Issue 12, pp. 2093-9, (2009) (PubMed).
: "Different subcellular localisations of TRIM22 suggest species-specific function." dans: Immunogenetics, Vol. 61, Issue 4, pp. 271-80, (2009) (PubMed).
: "TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus." dans: The Journal of general virology, Vol. 90, Issue Pt 3, pp. 536-45, (2009) (PubMed).
: "Identification of TRIM22 as a RING finger E3 ubiquitin ligase." dans: Biochemical and biophysical research communications, Vol. 374, Issue 3, pp. 502-6, (2008) (PubMed).
: "Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells." dans: Oncogene, Vol. 23, Issue 23, pp. 4050-9, (2004) (PubMed).
: "Molecular cloning of a new interferon-induced factor that represses human immunodeficiency virus type 1 long terminal repeat expression." dans: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14891-8, (1995) (PubMed).
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- TRIM22 (Tripartite Motif Containing 22 (TRIM22))
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Autre désignation
- TRIM22
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Sujet
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TRIM22 (Tripartite motif-containing protein 22) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a Bbox type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.
Synonyms: RNF94 (RING finger protein 94), STAF50 (50 kDa-stimulated trans-acting factor)
Antigène
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