ASPSCR1 anticorps

N° du produit ABIN967214

1 publication est disponible pour ce produit. L’anticorps anti-ASPSCR1 Monoclonal produit chez le not_set a été validé pour WB et ELISA. Il convient pour la détection de ASPSCR1 dans des échantillons provenant de Souris. }

Aperçu rapide pour ASPSCR1 anticorps (ABIN967214)

Antigène: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Reactivité: Souris

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp ASPSCR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ASPSCR1 anticorps

Specificité: Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.2%BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-ASPSCR1 (ABIN967214)

Bogan, Hendon, McKee, Tsao, Lodish: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." dans: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).

Détails sur ASPSCR1

Antigène: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Autre désignation: TUG

Sujet: The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominantnegative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

ID gène: 68938