HSP70 anticorps

N° du produit ABIN967447

Détail du produit anti-HSP70 anticorps

Antigène: HSP70 (Heat Shock Protein 70 (HSP70))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSP70 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Marque: BD Pharmingen™

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Purified Hsp70

Clone: 5G10

Isotype: IgG2b

Information d'application

Indications d'application: HeLa cervical carcinoma cells (ATCC CCL-2) are suggested as a positive control.

Commentaires:

Related Products: ABIN968535, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-HSP70 (ABIN967447)

Cyr, Langer, Douglas: "DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70." dans: Trends in biochemical sciences, Vol. 19, Issue 4, pp. 176-81, (1994) (PubMed).

Craig, Gross: "Is hsp70 the cellular thermometer?" dans: Trends in biochemical sciences, Vol. 16, Issue 4, pp. 135-40, (1991) (PubMed).

Singh, Yu: "Accumulation of a heat shock-like protein during differentiation of human erythroid cell line K562." dans: Nature, Vol. 309, Issue 5969, pp. 631-3, (1984) (PubMed).

Détails sur HSP70

Antigène: HSP70 (Heat Shock Protein 70 (HSP70))

Autre désignation: Hsp70 (HSP70 Produits)

Synonymes: anticorps APG-2, anticorps HS24/P52, anticorps HSPH2, anticorps RY, anticorps hsp70, anticorps hsp70RY, anticorps CG31354, anticorps HSP70, anticorps Hsp70Bb, anticorps hsp70B, anticorps hsp70Bb-prime, anticorps DmelCG5834, anticorps CG5834, anticorps HSPA1, anticorps HSP70B', anticorps HSPA6, anticorps ARABIDOPSIS HEAT SHOCK PROTEIN 70, anticorps ATHSP70, anticorps heat shock protein 70, anticorps LOC100305036, anticorps hsc70, anticorps Hsp70, anticorps Hsp70-1, anticorps Hsp70.1, anticorps hsp68, anticorps Hsp110, anticorps irp94, anticorps HSP70-2, anticorps HSPA1B, anticorps HSPA2, anticorps hsp70-5, anticorps HSP70-1, anticorps HSP70.1, anticorps HSP70.2, anticorps heat shock protein family A (Hsp70) member 4, anticorps CG5834 gene product from transcript CG5834-RA, anticorps heat shock protein 70, anticorps heat shock protein family A (Hsp70) member 6, anticorps heat shock 70kDa protein 2, anticorps heat shock 70 kD protein cognate, anticorps Hsp70 family chaperone, anticorps Heat shock protein 70, anticorps Heat shock protein 70, putative, anticorps heat shock protein 1B, anticorps heat shock protein family A member 4, anticorps heat shock 70kDa protein 1A, anticorps heat shock protein 1, anticorps Heat Shock Protein, anticorps heat shock cognate 70-kd protein, anticorps Heat shock 70 kDa protein 1A, anticorps HSPA4, anticorps Hsp70Bbb, anticorps HSP70, anticorps HSPA6, anticorps HSPA2, anticorps PCC7424_2419, anticorps Isop_1041, anticorps CGB_C3390W, anticorps Bacsa_1698, anticorps dnaK-B, anticorps LOC100305036, anticorps Hspa1b, anticorps Hspa4, anticorps HSPA1A, anticorps hsp1, anticorps hsp-70, anticorps hsp70, anticorps LOC108348108

Sujet: Cells from many organisms increase the expression of heat shock or stress proteins in response to adverse changes. The heat shock protein (HSP) 70 family consists of multiple members, localized within different intracellular compartments. HSP 70 is constitutively expressed in many human cells with increased expression observed following stress. Members of the HSP 70 family bind ATP, and are thought to function as molecular chaperones by assisting in the folding of other proteins in various intracellular compartments. HSP 70 migrates at a molecular weight of 70 kDa in SDS-PAGE. The 5G10 antibody recognizes human HSP 70. Purified HSP 70 was isolated from K562, a human erythroid cell line, and used as immunogen.

Poids moléculaire: 70 kDa