SELPLG anticorps

N° du produit ABIN967489

Cet anticorps Souris Monoclonal détecte spécifiquement SELPLG dans FACS, WB, IP et BR. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour SELPLG anticorps (ABIN967489)

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SELPLG est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Blocking Reagent (BR)

Clone: KPL-1

Détail du produit anti-SELPLG anticorps

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Références pour anticorps anti-SELPLG (ABIN967489)

Snapp, Ding, Atkins, Warnke, Luscinskas, Kansas: "A novel P-selectin glycoprotein ligand-1 monoclonal antibody recognizes an epitope within the tyrosine sulfate motif of human PSGL-1 and blocks recognition of both P- and L-selectin." dans: Blood, Vol. 91, Issue 1, pp. 154-64, (1998) (PubMed).

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: CD162

Sujet: Reacts with p-selectin glycoprotein ligand-1 (PSGL-1), a 120 - 220 kDa, mucin-like type I transmembrane glycoprotein. CD162 is expressed on neutrophils, monocytes, and most lymphocytes. CD162 binds to CD62P (P-Selectin), CD62E (E-Selectin) and CD62L (L-Selectin). This molecule mediates rolling of leukocytes on activated endothelium and the interaction between leukocytes and activated platelets or other leukocytes found at inflammatory sites. It has also been reported that this clone completely inhibits the interaction between P-Selectin and either CD4-T cells or neutrophils.
Synonyms: PSGL-1, p-selectin glycoprotein ligand-1