ANXA6 anticorps (AA 1-673)

N° du produit ABIN967890

Cité dans 5 publications. Cet anticorps anti-ANXA6 Monoclonal Souris (Clone 73-Annexin VI) (ABIN967890) détecte spécifiquement ANXA6 dans WB, IHC, IF et IP. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour ANXA6 anticorps (AA 1-673) (ABIN967890)

Antigène: ANXA6 (Annexin A6 (ANXA6))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ANXA6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 73-Annexin VI

Détail du produit anti-ANXA6 anticorps

Épitope: AA 1-673

Réactivité croisée: Rat (Rattus)

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human Annexin VI aa. 1-673

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN968537, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Références pour anticorps anti-ANXA6 (ABIN967890)

Chen, Coustan-Smith, Suzuki, Neale, Mihara, Pui, Campana: "Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia." dans: Blood, Vol. 97, Issue 7, pp. 2115-20, (2001) (PubMed).

Babiychuk, Draeger: "Annexins in cell membrane dynamics. Ca(2+)-regulated association of lipid microdomains." dans: The Journal of cell biology, Vol. 150, Issue 5, pp. 1113-24, (2000) (PubMed).

Babiychuk, Palstra, Schaller, Kämpfer, Draeger: "Annexin VI participates in the formation of a reversible, membrane-cytoskeleton complex in smooth muscle cells." dans: The Journal of biological chemistry, Vol. 274, Issue 49, pp. 35191-5, (2000) (PubMed).

Yu, Cassara, Weller: "Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells." dans: Blood, Vol. 95, Issue 3, pp. 1078-85, (2000) (PubMed).

Crompton, Moss, Crumpton: "Diversity in the lipocortin/calpactin family." dans: Cell, Vol. 55, Issue 1, pp. 1-3, (1988) (PubMed).

Détails sur ANXA6

Antigène: ANXA6 (Annexin A6 (ANXA6))

Autre désignation: Annexin VI

Sujet: Annexins are a widely expressed family of Ca[2+] and phospholipid-binding proteins. At least ten have been identified in mammalian tissues. They have also been identified in Drosophila, Hydra, and Dictyostelium. Annexin VI is a 70 kDa member of the annexin family. While most of the other annexin family members have a four amino acid sequence repeat, Annexin VI displays an eight residue repeat. It is a widely expressed protein, found in lymphocytes, neurons, and many other cell types. Work on annexins has addressed the possible role of Annexin VI in various stages of the endocytic pathway. Some studies suggest that Annexin VI is required for coated-vesicle budding. However, other research directly contradicts this data. Thus, the role of Annexin VI is still under investigation.

Poids moléculaire: 70 kDa