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Caveolin 3 anticorps (AA 3-24)

CAV3 Reactivité: Souris, Rat, Lapin WB, IHC, IP, IF Hôte: Souris Monoclonal 26-Caveolin 3 unconjugated
N° du produit ABIN967959
  • Antigène Voir toutes Caveolin 3 (CAV3) Anticorps
    Caveolin 3 (CAV3)
    Épitope
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 3-24
    Reactivité
    • 41
    • 24
    • 22
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris, Rat, Lapin
    Hôte
    • 39
    • 3
    • 1
    Souris
    Clonalité
    • 31
    • 12
    Monoclonal
    Conjugué
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Cet anticorp Caveolin 3 est non-conjugé
    Application
    • 20
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
     Réactivité croisée
    Souris, Lapin
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Rat Caveolin 3 aa. 3-24
    Clone
    26-Caveolin 3
    Isotype
    IgG1
    Top Product
    Discover our top product CAV3 Anticorps primaire
  • Indications d'application
    This antibody was tested in development by immunohistochemistry using the SDS Antigen Retreival Method.
    Commentaires

    Related Products: ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20°C.
  • Lavitrano, Bacci, Forni, Lazzereschi, Di Stefano, Fioretti, Giancotti, Marfé, Pucci, Renzi, Wang, Stoppacciaro, Stassi, Sargiacomo, Sinibaldi, Turchi, Giovannoni, Della Casa, Seren, Rossi: "Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 22, pp. 14230-5, (2002) (PubMed).

    Woodman, Park, Cohen, Cheung, Chandra, Shirani, Tang, Jelicks, Kitsis, Christ, Factor, Tanowitz, Lisanti: "Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade." dans: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38988-97, (2002) (PubMed).

    Zhao, Liu, Stan, Fan, Gu, Dalton, Chu, Peterson, Ross, Chien: "Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 17, pp. 11375-80, (2002) (PubMed).

    Rybin, Xu, Lisanti, Steinberg: "Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway." dans: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41447-57, (2001) (PubMed).

    Song, Scherer, Tang, Okamoto, Li, Chafel, Chu, Kohtz, Lisanti: "Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins." dans: The Journal of biological chemistry, Vol. 271, Issue 25, pp. 15160-5, (1996) (PubMed).

  • Antigène
    Caveolin 3 (CAV3)
    Autre désignation
    Caveolin 3 (CAV3 Produits)
    Synonymes
    anticorps LGMD1C, anticorps LQT9, anticorps VIP-21, anticorps VIP21, anticorps AI385751, anticorps Cav-3, anticorps M-cav, anticorps caveolin-3, anticorps im:6902906, anticorps zgc:109710, anticorps LOC733765, anticorps CAV3, anticorps cav3, anticorps caveolin 3, anticorps caveolin-3, anticorps CAV3, anticorps Cav3, anticorps cav3, anticorps LOC733765, anticorps cav-3
    Sujet
    Identified as a tyrosine phosphorylated protein in Rous sarcoma virus-transformed chick embryo fibroblasts (CEF), caveolin is now known to be ubiquitously expressed. Caveolin (also known as VIP21) localizes to non-clathrin membrane invaginations (caveolae) on the inner surface of the plasma membrane. This transmembrane protein plays a structural role in these specializations. Caveolin is also present at the trans-Golgi network (TGN), and similar quantities are found in apically and basolaterally destined transport vesicles. Caveolin is part of a complex containing glycosylphosphatidylinositol (GPI)-linked molecules and cytoplasmic signaling proteins. Caveolin is a transmembrane adaptor molecule that can simultaneously recognize GPI-linked proteins and interact with downstream cytoplasmic signaling molecules, such as c-yes, Annexin II, and hetero-trimeric G proteins. Caveolin 3 has been identified as a distinct isoform which is expressed only in smooth, skeletal, and cardiac muscle.
    Poids moléculaire
    18 kDa
    Pathways
    Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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