GLN1 anticorps (AA 1-373)

N° du produit ABIN968014

Cet anticorps Souris Monoclonal détecte spécifiquement GLN1 dans WB, IHC, IP, IF et BI. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 11+ publications.

Aperçu rapide pour GLN1 anticorps (AA 1-373) (ABIN968014)

Antigène: GLN1 (Glutamine Synthetase (GLN1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GLN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), BioImaging (BI)

Clone: 6-Glutamine Synthetase

Détail du produit anti-GLN1 anticorps

Épitope: AA 1-373

Réactivité croisée: Rat (Rattus), Humain, Souris

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human Glutamine Synthetase aa. 1-373

Isotype: IgG2a

Information d'application

Commentaires:

Related Products: ABIN968545, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Références pour anticorps anti-GLN1 (ABIN968014)

Puller, Haverkamp: "Cell-type-specific localization of protocadherin β16 at AMPA and AMPA/Kainate receptor-containing synapses in the primate retina." dans: The Journal of comparative neurology, Vol. 519, Issue 3, pp. 467-79, (2011) (PubMed).

Kawano, Tanizawa, Shinoda: "Wolfram syndrome 1 (Wfs1) gene expression in the normal mouse visual system." dans: The Journal of comparative neurology, Vol. 510, Issue 1, pp. 1-23, (2008) (PubMed).

Poché, Furuta, Chaboissier, Schedl, Behringer: "Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development." dans: The Journal of comparative neurology, Vol. 510, Issue 3, pp. 237-50, (2008) (PubMed).

Gaillard, Bonfield, Gilmour, Kuny, Mema, Martin, Smale, Crowder, Stell, Sauvé: "Retinal anatomy and visual performance in a diurnal cone-rich laboratory rodent, the Nile grass rat (Arvicanthis niloticus)." dans: The Journal of comparative neurology, Vol. 510, Issue 5, pp. 525-38, (2008) (PubMed).

Ding, Weinberg: "Distribution of soluble guanylyl cyclase in rat retina." dans: The Journal of comparative neurology, Vol. 500, Issue 4, pp. 734-45, (2007) (PubMed).

Sullivan, Benton, Sandeman, Beltz: "Adult neurogenesis: a common strategy across diverse species." dans: The Journal of comparative neurology, Vol. 500, Issue 3, pp. 574-84, (2007) (PubMed).

Kronfeld, Kazimirsky, Lorenzo, Garfield, Blumberg, Brodie: "Phosphorylation of protein kinase Cdelta on distinct tyrosine residues regulates specific cellular functions." dans: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35491-8, (2000) (PubMed).

Labow, Souba, Abcouwer: "Glutamine synthetase expression in muscle is regulated by transcriptional and posttranscriptional mechanisms." dans: The American journal of physiology, Vol. 276, Issue 6 Pt 1, pp. E1136-45, (1999) (PubMed).

Fei, DAmbrosio, Li, Surmacz, Baserga: "Association of insulin receptor substrate 1 with simian virus 40 large T antigen." dans: Molecular and cellular biology, Vol. 15, Issue 8, pp. 4232-39, (1995) (PubMed).

Kentroti, Baker, Lee, Bruce, Vernadakis: "Platelet-activating factor increases glutamine synthetase activity in early and late passage C-6 glioma cells." dans: Journal of neuroscience research, Vol. 28, Issue 4, pp. 497-506, (1991) (PubMed).

Vardimon, Fox, Cohen-Kupiec, Degenstein, Moscona: "Expression of v-src in embryonic neural retina alters cell adhesion, inhibits histogenesis, and prevents induction of glutamine synthetase." dans: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5275-84, (1991) (PubMed).

Détails sur GLN1

Antigène: GLN1 (Glutamine Synthetase (GLN1))

Autre désignation: Glutamine Synthetase

Sujet: Glutamine synthetase catalyzes the amination of glutamic acid to form glutamine. It is found in mammals as an octamer of identical 45 kDa subunits. Glutamine synthetase activity is a useful marker for astrocytes and an important differentiation feature in retina. It is also considered to be a key enzyme in the recycling of the neurotransmitter glutamate. This antibody is routinely tested by western blot analysis.

Poids moléculaire: 45 kDa

Pathways: Positive Regulation of Peptide Hormone Secretion